Wednesday, November 4, 2026Updated every morning at 5:30 AM ET
NanotechProgress

Intellia Therapeutics

Develops CRISPR gene-editing treatments delivered into the body by lipid nanoparticles, led by nex-z.

NeurologyLive, 28 Jan 2026

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Ticker
NTLA · Nasdaq
Based in
United States
Website
intelliatx.com ↗

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On the record

Latest steps

The newest dated events on the technologies above.

  1. Human trial

    In-body gene editing

    The FDA lifted the hold on MAGNITUDE-2, the trial in the nerve form of the disease, with closer monitoring of liver tests. The hold on the heart trial, MAGNITUDE, stayed.

    NeurologyLive, 28 Jan 2026
  2. Setback

    In-body gene editing

    The FDA put Intellia's two phase 3 trials of nex-z on hold after a patient had severe liver injury. The patient died on November 5, 2025.

    NeurologyLive, 28 Jan 2026
  3. Human trial

    In-body gene editing

    Doctors at Children's Hospital of Philadelphia and Penn Medicine treated a baby, KJ, born with a rare metabolic disease, with a gene-editing therapy made just for him and delivered to his liver in lipid nanoparticles. It was given safely, and he is growing well. The case was published in the New England Journal of Medicine.

    Children's Hospital of Philadelphia, 15 May 2025

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