Albumin-bound paclitaxel (Abraxane)
Abraxane is the cancer drug paclitaxel bound to albumin, a human blood protein, in the form of nanoparticles. Approved in 2005 for breast cancer that has spread, it was the first of a new class of albumin-bound nanomedicines.
News-Medical, 9 Jan 2005How far from your life: You can get it now, though it may not be common yet.
Independently sourcedFrom lab to your life
Why it’s on step 4
- 1Lab discovery
- 2Working prototype
- 3Real-world testing
- 4Approved or on sale
- 5Everyday life
The rule
A regulator approved or cleared it where approval applies (the FDA, the EMA, a CE mark), or it is sold to the public or to customers beyond a trial.
- The FDA approved Abraxane for breast cancer that has spread, the first of a new class of albumin-bound nanoparticle drugs. News-Medical, 9 Jan 2005
The short version
What you need to know
- Why it matters
The older form of paclitaxel is dissolved in a solvent that can cause dangerous allergic reactions, so patients first need steroids. The nanoparticle form doesn't need them.
News-Medical, 9 Jan 2005- Is it really nano?
Truly nano
The protein nanoparticle replaces the harsh solvent the older drug needs; that is the whole difference.
News-Medical, 9 Jan 2005- Where you’ll find it
Given in cancer clinics, first approved for breast cancer that has spread.
News-Medical, 9 Jan 2005- Who’s behind it
Developed by American Pharmaceutical Partners; now sold by Bristol Myers Squibb
On the record
Every step, dated
Newest first. Company-reported means the only source so far is the company itself.
- Approval
The FDA approved Abraxane for breast cancer that has spread, the first of a new class of albumin-bound nanoparticle drugs.
News-Medical, 9 Jan 2005
Sources
Where every line comes from
Each source with the passage, word for word, that backs what we wrote.
- News-Medical, 9 Jan 2005
the first in a new class of albumin-bound nanotechnology, was approved for the treatment of metastatic breast cancer.
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