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NanotechProgress

DNA origami

DNA origami folds a long strand of DNA into chosen shapes and patterns a few nanometers in size, held in place by short DNA strands, like a pegboard on which other molecules can be placed exactly.

Caltech, 10 Mar 2016
Building with DNA · how far it has got1/5Lab discovery

How far from your life: Usually 10 years or more from products, and most never get there.

Independently sourced

From lab to your life

Why it’s on step 1

  1. 1Lab discovery
  2. 2Working prototype
  3. 3Real-world testing
  4. 4Approved or on sale
  5. 5Everyday life

The rule

Shown in a lab or a computer model, in a published paper or preprint, with nothing on record beyond it yet.

  • Paul Rothemund of Caltech published his method for folding DNA into shapes and patterns a few nanometers in size, in Nature. Caltech, 10 Mar 2016

The short version

What you need to know

Why it matters

It lets researchers arrange proteins, gold particles or nanotubes in precise patterns that no other method can make, for example as tiny assembly lines of enzymes.

Caltech, 10 Mar 2016
How small

Its famous smiley faces are each about a thousandth of the width of a human hair.

Caltech, 10 Mar 2016
Is it really nano?

Truly nano

The shapes are built and measured in nanometers.

Caltech, 10 Mar 2016
Who’s behind it

Invented by Paul Rothemund at Caltech; used in labs worldwide

On the record

Every step, dated

Newest first. Company-reported means the only source so far is the company itself.

  1. Published research

    Paul Rothemund of Caltech published his method for folding DNA into shapes and patterns a few nanometers in size, in Nature.

    Caltech, 10 Mar 2016